General Cell Lines and Cell Cultures
Eurofins Discoverx KILR U118-MG Cell Pool, 2 vials. (97-1018P032)
The KILR U118-MG cell pool is a stable, engineered target cell pool, which closely reflects the heterogeneous native protein expression of tumor environments, used to measure direct cell death mediated by immunooncology treatments (e.g. checkpoint modulators, bispecifics, CAR-T, etc.) via Antibody Dependent Cell-mediated Cytotoxicity (ADCC), Complement Dependent Cytotoxicity (CDC), and Antibody Dependent Cell Phagocytosis (ADCP). This product uses EFC technology. The cell pool is a heterogeneous population of U118-MG cells that overexpress a ProLabel-tagged housekeeping gene. Upon effector cells-mediated cell lysis, ProLabel is released to the media, where EA in the detection kit produces an EFC signal proportional to the level of ProLabel released. This allows for calculation of percent lysis of the KILR cell pool. This stable cell pool is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kilr.
Eurofins Discoverx ChemiScreen S1P1 Lysophospholipid Receptor Stable Cell Line, 2 vials. (HTS176C)
The ChemiScreen S1P1 Lysophospholipid Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. S1P) based activation of S1PR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses S1PR1 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of S1PR1, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
ATCC Quantitative Genomic DNA from; Clostridium perfringens; Strain: NCTC 8237
Quantitative genomic DNA from Clostridium perfringens strain NCTC 8237 (ATCC 13124) can be used for assay development, verification, validation, and monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load.
ATCC Saccharomyces cerevisiae; S288C
An ampoule containing viable cells suspended in cryoprotectant.
ATCC Hepatitis A virus; Strain: HM175/18f
Hepatitis A virus strain HM175/18f is propagated in FRhK-4 cells (ATCC CRL-1688). The virus was isolated in the agarose of a radioimmunofocus assay in FRhK-4 cells and was subsequently passaged in BS-C-1 cells. The strain has applications in enteric and infectious disease research.
ATCC Primary Coronary Artery Endothelial Cells; Normal, Human
ATCC Normal Human Primary Coronary Artery Endothelial Cells, when grown in Vascular Cell Basal Media supplemented with Endothelial Cell Growth Kit components, provide an ideal cell system to propagate coronary artery endothelial cells in low serum conditions with or without the addition of human recombinant VEGF.
ATCC Quantitative Synthetic; West Nile; Virus RNA
Synthetic West Nile virus RNA can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine viral load. This preparation includes fragments from the 5’ UTR, capsid, membrane glycoprotein precursor (prM), Envelope protein (ENV), Nonstructural protein NS1, Nonstructural protein NS2A, Nonstructural protein NS3, RNA-dependent RNA polymerase NS5, and 3’ UTR regions.
Biolegend Brilliant Violet 605TM anti-hu
Brilliant Violet 605™ anti-human CD192 (CCR2) [K036C2]; Isotype: Mouse IgG2a, κ; Reactivity: Human; Apps: FC; Size: 100 tests
Montana Molecular Borealis Arrestin KOR Assay - 10mL
Measure arrestin signaling kinetics in real time with the live cell, fluorescent Borealis arrestin - Kappa Opioid receptor (KOR) assay. Add the unmodified KOR and Borealis sensor to cells and measure robust signals the next day on an automated plate reader or fluorescence imaging system. This assay is genetically encoded and packaged in BacMam for efficient transduction in most cell types - including uniform and near 100% efficiency in HEK293 cells as well as expression in many primary or iPSC-derived cells. The kit includes the arrestin sensor BacMam, KOR BacMam, GRK5 BacMam, 500mM sodium butyrate in H2O, and a positive control receptor and agonist (AT1R BacMam and 5mM Angiotensin II in H2O). Borealis kits for several other receptors are also available, and larger-sized kits are available on request. Other Montana Molecular tools including the cADDis cAMP sensor can be used alongside this assay.
ATCC Quantitative Genomic DNA from; Proteus vulgaris; Strain: CDC PR1
ATCC Genuine Nucleics can be used for assay development, verification, validation, monitoring of day-to-day test variation, and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load.
Amsbio LLC Lyophilized microvesicles from LnCAP-1 cell line
Lyophilized microvesicles from LnCAP-1 cell line
ATCC Staphylococcus aureus; subsp. aureus; Quantitative DNA
ATCC Genuine Nucleics can be used for assay development, verification, validation, monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load and for other molecular biology applications.
ATCC Hs 729T; Rhabdomyosarcoma; Human (Homo sapiens)
Hs 729 [Hs 729T] is a fibroblast cell that was isolated from the muscle of a 74-year-old, White, male with rhabdomyosarcoma.
ATCC Streptomyces scabiei
Streptomyces scabiei strain RL-34 is a bacterial type strain that was isolated from a potato in New York.
